Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs
- 1 July 1985
- journal article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 316 (6024), 126-131
- https://doi.org/10.1038/316126a0
Abstract
We describe a new class of drugs that selectively block serotonin M-receptors on peripheral neurones. Because of their high affinity, some of these drugs are the most potent of any pharmacological class yet reported. They have allowed the identification of three M-receptor subtypes, one of which is responsible for mediating the painful effects of serotonin in humans.This publication has 24 references indexed in Scilit:
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