Active Site Mutations Define the Pathway for the Cooperative Activation of cAMP-Dependent Protein Kinase
- 1 January 1996
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 35 (9), 2934-2942
- https://doi.org/10.1021/bi951647c
Abstract
No abstract availableKeywords
This publication has 11 references indexed in Scilit:
- Ala335is essential for high-affinity cAMP-binding of both sites A and B of cAMP-dependent protein kinase type IFEBS Letters, 1995
- Mutations in the autoinhibitor site of the regulatory subunit of cAMP-dependent protein kinase I. Replacement of Ala-97 and Ser-99 interferes with reassociation with the catalytic subunitJournal of Biological Chemistry, 1991
- cAMP-DEPENDENT PROTEIN KINASE: FRAMEWORK FOR A DIVERSE FAMILY OF REGULATORY ENZYMESAnnual Review of Biochemistry, 1990
- Expression of the Catalytic Subunit of cAMP-Dependent Protein Kinase in Escherichia coliPublished by Elsevier BV ,1989
- Deletion of cAMP-binding site B in the regulatory subunit of cAMP-dependent protein kinase alters the photoaffinity labeling of site A.Published by Elsevier BV ,1988
- Deletion mutants as probes for localizing regions of subunit interaction in cAMP-dependent protein kinase.Published by Elsevier BV ,1988
- Antiparallel alignment of the two protomers of the regulatory subunit dimer of cAMP-dependent protein kinase I.Published by Elsevier BV ,1987
- Expression of the type I regulatory subunit of cAMP-dependent protein kinase in Escherichia coli.Journal of Biological Chemistry, 1986
- Effect of Cyclic Nucleotide Analogs on Intrachain Site 1 of Protein Kinase IsozymesEuropean Journal of Biochemistry, 1982
- Protein kinase II has two distinct binding sites for cyclic AMP, only one of which is detectable by the conventional membrane‐filtration methodFEBS Letters, 1980