Recrudescence of Focal Stroke Symptoms during Pain Management with Hydromorphone
Open Access
- 31 March 2016
- journal article
- case report
- Published by Frontiers Media SA in Frontiers in Neurology
- Vol. 7, 50
- https://doi.org/10.3389/fneur.2016.00050
Abstract
Patients who have recovered from a prior stroke may experience a reemergence of their original stroke syndrome secondary to metabolic derangements, sedation, infection, and/or fatigue. Critically, the molecular/cellular mechanisms mediating symptom recurrence after exposure to analgesic agents remain unknown. Accordingly, herein we report a unique case of a patient with hydromorphone-induced recrudescence 30 years after her initial stroke event(s), and in so doing propose a putative mechanism related to post-infarction functional neuroplasticity.Funding Information
- National Institute of Neurological Disorders and Stroke
- National Institutes of Health
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