Towards a dietary-exposome assessment of chemicals in food: An update on the chronic health risks for the European consumer
Open Access
- 16 May 2019
- journal article
- review article
- Published by Informa UK Limited in Critical Reviews in Food Science and Nutrition
- Vol. 60 (11), 1890-1911
- https://doi.org/10.1080/10408398.2019.1612320
Abstract
An informed opinion to a hugely important question, whether the food on the Europeans’ plate is safe to eat, is provided. Today, the Europeans face food-borne health risks from non-communicable diseases induced by excess body weight, outbreaks caused by pathogens, antimicrobial resistance and exposures to chemical contaminants. In this review, these risks are first put in an order of importance. Then, not only potentially injurious dietary chemicals are discussed but also beneficial factors of the food. This review can be regarded as an attempt towards a dietary-exposome evaluation of the chemicals, the average European adult consumers could chronically expose to during their life-times. Risk ranking reveals that currently the European adults are chronically exposed to a mixture of potentially genotoxic-carcinogenic contaminants, particularly food process contaminants, at the potential risk levels. Furthermore, several of the contaminants whose dietary exposures pose risks appear to be carcinogens operating with a genotoxic mode of action targeting the liver. This suggests that combined health risks from the exposure to a mixture of the chemical contaminants poses a greater potential risk than the risks assessed for single compounds. Over 100 European-level risk assessments are examined. Finally, the importance of a diversified and balanced diet is emphasized.Keywords
Funding Information
- European Union Horizon (692195)
This publication has 135 references indexed in Scilit:
- Association between Plasma PFOA and PFOS Levels and Total Cholesterol in a Middle-Aged Danish PopulationPLOS ONE, 2013
- Consumer response to novel agri-food technologies: Implications for predicting consumer acceptance of emerging food technologiesTrends in Food Science & Technology, 2011
- Exposure to Polyfluoroalkyl Chemicals and Cholesterol, Body Weight, and Insulin Resistance in the General U.S. PopulationEnvironmental Health Perspectives, 2010
- Blood Cadmium and Lead and Chronic Kidney Disease in US Adults: A Joint AnalysisAmerican Journal of Epidemiology, 2009
- Furan-induced dose–response relationships for liver cytotoxicity, cell proliferation, and tumorigenicity (furan-induced liver tumorigenicity)Experimental and Toxicologic Pathology, 2009
- Well Water Arsenic Exposure, Arsenic Induced Skin-Lesions and Self-Reported Morbidity in Inner MongoliaInternational Journal of Environmental Research and Public Health, 2009
- Urinary Cadmium and Osteoporosis in U.S. Women ≥50 Years of Age: NHANES 1988–1994 and 1999–2004Environmental Health Perspectives, 2008
- Bone Resorption and Environmental Exposure to Cadmium in Women: A Population StudyEnvironmental Health Perspectives, 2008
- Neonatal exposure to the brominated flame-retardant, 2,2′,4,4′,5-pentabromodiphenyl ether, decreases cholinergic nicotinic receptors in hippocampus and affects spontaneous behaviour in the adult mouseEnvironmental Toxicology and Pharmacology, 2004
- Low-Level Cadmium Exposure and OsteoporosisJournal of Bone and Mineral Research, 2000