Burden of Disease Caused by Otitis Media: Systematic Review and Global Estimates
Top Cited Papers
Open Access
- 30 April 2012
- journal article
- review article
- Published by Public Library of Science (PLoS) in PLOS ONE
- Vol. 7 (4), e36226
- https://doi.org/10.1371/journal.pone.0036226
Abstract
Otitis media (OM) is a leading cause of health care visits and drugs prescription. Its complications and sequelae are important causes of preventable hearing loss, particularly in developing countries. Within the Global Burden of Diseases, Injuries, and Risk Factors Study, for the year 2005 we estimated the incidence of acute OM, chronic suppurative OM, and related hearing loss and mortality for all ages and the 21 WHO regional areas. We identified risk factors, complications and sequelae of OM. We carried out an extensive literature review (Medline, Embase, Lilacs and Wholis) which lead to the selection of 114 papers comprising relevant data. Data were available from 15 of the 21 WHO regions. To estimate incidence and prevalence for all countries we adopted a two stage approach based on risk factors formulas and regression modelling. Acute OM incidence rate is 10.85% i.e. 709million cases each year with 51% of these occurring in under-fives. Chronic suppurative OM incidence rate is 4.76‰ i.e. 31million cases, with 22.6% of cases occurring annually in under-fives. OM-related hearing impairment has a prevalence of 30.82 per ten-thousand. Each year 21thousand people die due to complications of OM. Our study is the first attempt to systematically review the available information and provide global estimates for OM and related conditions. The overall burden deriving from AOM, CSOM and their sequelae is considerable, particularly in the first five years of life and in the poorest countries. The findings call for incorporating OM-focused action within preventive and case management strategies, with emphasis on the more affected.Keywords
This publication has 49 references indexed in Scilit:
- Chronic suppurative otitis media in children of Luanda, AngolaActa Paediatrica, 2011
- Cost Effectiveness of Pneumococcal Conjugate Vaccination against Acute Otitis Media in ChildrenPharmacoEconomics, 2011
- Treatment of Acute Otitis Media in Children under 2 Years of AgeThe New England Journal of Medicine, 2011
- The emergence of Cognitive Hearing ScienceScandinavian Journal of Psychology, 2009
- The incidence, prevalence and burden of OM in unselected children aged 1–8 years followed by weekly otoscopy through the “common cold” seasonInternational Journal of Pediatric Otorhinolaryngology, 2008
- Perda auditiva sensório-neural na otite média crônica supurativa em pacientes com e sem colesteatomaRevista Brasileira de Otorrinolaringologia, 2007
- Otitis Media, Hearing Loss, and Language LearningJournal of Developmental & Behavioral Pediatrics, 2004
- Sensorineural Hearing Loss in Chronic Otitis MediaOtology & Neurotology, 2003
- Health effects of passive smoking 10: Summary of effects of parental smoking on the respiratory health of children and implications for researchThorax, 1999
- Otitis Media in Infancy and Intellectual Ability, School Achievement, Speech, and Language at Age 7 YearsThe Journal of Infectious Diseases, 1990