Original article: Frequency and impact of allergic rhinitis in asthma patients in everyday general medical practice: a French observational cross‐sectional study
- 4 February 2008
- Vol. 63 (3), 292-298
- https://doi.org/10.1111/j.1398-9995.2007.01584.x
Abstract
Allergic rhinitis (AR) and asthma are inflammatory conditions of the airways that often occur concomitantly. This observational, cross-sectional, national study was undertaken to describe the frequency and severity of AR in asthmatic patients. The impact of AR on the quality of life and the therapeutic management of patients in everyday general medical practice were also assessed. From April to October 2005, 1906 French general practitioners (GP) participated in the study. Each physician had to fill out a questionnaire (including the Juniper Asthma Control Questionnaire and a Rhinitis Questionnaire) for up to 10 consecutive adult asthmatic patients. The first three patients with a confirmed diagnosis of AR (Allergic Rhinitis and its Impact on Asthma classification) were asked to complete the Juniper Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ). A total of 14,703 patient questionnaires and 4335 auto-questionnaires were analysed. Patients presented with intermittent (45%), mild (25%), moderate (25%) and severe (4%) persistent asthma. The frequency of AR in asthmatic patients was 55.2% (CI: 95%, 54.4-56.0%). Allergic rhinitis was mild for 54% and moderate/severe for 46% of patients. The frequency and severity of AR increased with the severity of asthma (P < 0.001). Moreover, AR was associated with worse asthma control whatever be the severity of asthma (P < 0.001). The global RQLQ scores of AR patients worsened with the severity of asthma (P < 0.001). Prescription of anti-asthma treatments significantly increased with the severity of AR. The majority of AR patients (81%) were treated for rhinitis. This survey suggested that AR was associated with more severe asthma, more difficulty to control asthma and substantial impairment of quality of life. The high frequency of AR in asthma patients requires that these conditions should be recognized and managed by GP.Keywords
This publication has 29 references indexed in Scilit:
- Undertreatment of rhinitis symptoms in Europe: findings from a cross‐sectional questionnaire surveyAllergy, 2007
- Allergic rhinitis and asthma ad hoc survey: clinical and psychological perspectivesClinical and Experimental Allergy, 2007
- The Impact of Comorbid Atopic Disease on Asthma: Clinical Expression and TreatmentJournal of Asthma, 2007
- Survey on the impact of comorbid allergic rhinitis in patients with asthmaBMC Pulmonary Medicine, 2006
- The diagnosis of asthma using a self-questionnaire in those suffering from allergic rhinitis: a pharmaco-epidemiological survey in everyday practice in FranceAllergy, 2006
- Burden of Concomitant Allergic Rhinitis in Adults with AsthmaJournal of Asthma, 2006
- Association between asthma and rhinitis according to atopic sensitization in a population-based studyJournal of Allergy and Clinical Immunology, 2004
- Development and validation of a questionnaire to measure asthma controlEuropean Respiratory Journal, 1999
- Measuring health-related quality of life in rhinitis☆☆☆★Journal of Allergy and Clinical Immunology, 1997
- International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methodsEuropean Respiratory Journal, 1995