Inhibition of Lysine Acetyltransferase KAT3B/p300 Activity by a Naturally Occurring Hydroxynaphthoquinone, Plumbagin
Open Access
- 1 September 2009
- journal article
- Published by Elsevier BV
- Vol. 284 (36), 24453-24464
- https://doi.org/10.1074/jbc.m109.023861
Abstract
No abstract availableKeywords
This publication has 36 references indexed in Scilit:
- Mechanism of p300 Specific Histone Acetyltransferase Inhibition by Small MoleculesJournal of Medicinal Chemistry, 2008
- The Natural Naphthoquinone Plumbagin Exhibits Antiproliferative Activity and Disrupts the Microtubule Network through Tubulin BindingBiochemistry, 2008
- Activation of p53 Function by Human Transcriptional Coactivator PC4: Role of Protein-Protein Interaction, DNA Bending, and Posttranslational ModificationsMolecular and Cellular Biology, 2007
- Autoacetylation Induced Specific Structural Changes in Histone Acetyltransferase Domain of p300: Probed by Surface Enhanced Raman SpectroscopyThe Journal of Physical Chemistry B, 2007
- Selective Inhibition of CBP/p300 HATCell Chemical Biology, 2007
- Activation of p300 Histone Acetyltransferase by Small Molecules Altering Enzyme Structure: Probed by Surface-Enhanced Raman SpectroscopyThe Journal of Physical Chemistry B, 2007
- The Transcriptional Coactivator p300 Plays a Critical Role in the Hypertrophic and Protective Pathways Induced by Phenylephrine in Cardiac Cells but Is Specific to the Hypertrophic Effect of UrocortinChemBioChem, 2005
- Histone AcetyltransferasesAnnual Review of Biochemistry, 2001
- Histone acetyltransferase complexesSeminars in Cell & Developmental Biology, 1999
- DNA damage activates p53 through a phosphorylation–acetylation cascadeGenes & Development, 1998