Guideline for the prevention of acute nausea and vomiting due to antineoplastic medication in pediatric cancer patients
Open Access
- 19 March 2013
- journal article
- practice guideline
- Published by Wiley in Pediatric Blood & Cancer
- Vol. 60 (7), 1073-1082
- https://doi.org/10.1002/pbc.24508
Abstract
This guideline provides an approach to the prevention of acute antineoplastic‐induced nausea and vomiting (AINV) in children. It was developed by an international, inter‐professional panel using AGREE and CAN‐IMPLEMENT methods. Evidence‐based interventions that provide optimal AINV control in children receiving antineoplastic agents of high, moderate, low, and minimal emetogenicity are recommended. Recommendations are also made regarding selection of antiemetic agents for children who are unable to receive corticosteroids for AINV control, the role of aprepitant and optimal doses of antiemetic agents. Gaps in the evidence used to support the recommendations were identified. The contribution of this guideline to AINV control in children requires prospective evaluation. Pediatr Blood Cancer 2013; 60: 1073–1082.Funding Information
- Pediatric Oncology Group of Ontario
- Ministry of Health and Long Term Care, Ontario
- Children's Oncology Group
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