Early-Onset Macular Degeneration with Drusen in a Cynomolgus Monkey (Macaca fascicularis) Pedigree: Exclusion of 13 Candidate Genes and Loci

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Abstract
Purpose. To describe hereditary macular degeneration observed in the cynomolgus monkey (Macaca fascicularis), which shares phenotypic features with age-related macular degeneration in humans, and to test the involvement of candidate gene loci by mutation screening and linkage analysis.