Cloning, characterization and expression of the gene encoding cytochrome P-450sca-in2 from Streptomyces carbophilus involved in production of pravastatin, a specific HMG-CoA reductase inhibitor
- 22 September 1995
- journal article
- research article
- Published by Elsevier BV in Gene
- Vol. 163 (1), 81-85
- https://doi.org/10.1016/0378-1119(95)00394-l
Abstract
No abstract availableKeywords
This publication has 9 references indexed in Scilit:
- Phenobarbital and sulfonylurea-inducible operons encoding herbicide metabolizing cytochromes P-450 in Streptomyces griseolusGene, 1992
- A two component-type cytochrome P-450 monooxygenase system in a prokaryote that catalyzes hydroxylation of ML-236B to pravastatin, a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductaseBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1991
- Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitorBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1990
- Genes for two herbicide-inducible cytochromes P-450 from Streptomyces griseolusJournal of Bacteriology, 1990
- Purification and characterization of cytochrome P‐450sca from Streptomyces carbophilusEuropean Journal of Biochemistry, 1989
- CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal speciesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1986
- Microbial hydroxylation of ML-236B (compactin) and monacolin K (MB-530B)The Journal of Antibiotics, 1983
- Microbial hydroxylation of ML-236B (compactin) Studies on microorganisms capable of 3.BETA.-hydroxylation of ML-236B.The Journal of Antibiotics, 1983
- Isolation of biologically active ribonucleic acid from sources enriched in ribonucleaseBiochemistry, 1979