Continuation Rates and Complications of Intrauterine Contraception in Women Diagnosed With Bipolar Disorder
Open Access
- 1 December 2011
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Obstetrics & Gynecology
- Vol. 118 (6), 1331-1336
- https://doi.org/10.1097/aog.0b013e318233beae
Abstract
To estimate continuation rates, complications, and psychiatric hospitalizations among women with bipolar disorder using levonorgestrel-releasing or copper-containing intrauterine devices (IUDs) as compared with those using depot medroxyprogesterone acetate or sterilization for birth control. Data for this cohort study were obtained from a nationwide health insurance claims database on an employed, commercially insured population. Women aged 18–44 years with a prior diagnosis of bipolar disorder (n=849) who were using the levonorgestrel intrauterine system, a copper-containing IUD, depot medroxyprogesterone acetate, or sterilization were evaluated. Outcomes included continuation rates over a 12-month interval, infectious and noninfectious complications, and hospitalizations for bipolar disorder or depression. Women using an IUD were more likely than those using depot medroxyprogesterone acetate to continue the method for at least 12 months (copper-containing IUD, 86%; levonorgestrel intrauterine system, 87%). In comparison, only 31% of those who initiated depot medroxyprogesterone acetate received three more injections during the next year (P More women with bipolar disorder continued using IUDs at one year than women using depot medroxyprogesterone acetate. The rates of complications and psychiatric hospitalizations were not different among women using an IUD, depot medroxyprogesterone acetate, or sterilization. IIKeywords
This publication has 28 references indexed in Scilit:
- Continuation and Satisfaction of Reversible ContraceptionObstetrics & Gynecology, 2011
- One-Year Contraceptive Continuation and Pregnancy in Adolescent Girls and Women Initiating Hormonal ContraceptivesObstetrics & Gynecology, 2011
- Use of contraceptive methods among women treated for bipolar disorderArchives of Women's Mental Health, 2009
- Discontinuation and resumption of contraceptive use: results from the 2002 National Survey of Family GrowthContraception, 2008
- Physiologic and psychologic symptoms associated with use of injectable contraception and 20 μg oral contraceptive pillsAmerican Journal of Obstetrics and Gynecology, 2008
- HIV risk behavior among patients with co-occurring bipolar and substance use disorders: Associations with mania and drug abuseDrug and Alcohol Dependence, 2008
- Lifetime and 12-Month Prevalence of Bipolar Spectrum Disorder in the National Comorbidity Survey ReplicationArchives of General Psychiatry, 2007
- Serious ventricular arrhythmias among users of cisapride and other QT‐prolonging agents in the United StatesPharmacoepidemiology and Drug Safety, 2002
- Depot medroxyprogesterone acetate: Patterns of use and reasons for discontinuationContraception, 1997
- Use of insurance claims in epidemiologic research: Identification of peptic ulcers, gi bleeding, pancreatitis, hepatitis and renal diseasePharmacoepidemiology and Drug Safety, 1995