The Electrophoretic Phenotypes of Red Cell Phosphoglucomutase, Adenylate Kinase, and Acid Phosphatase in the American Negro

Abstract

A close similarity exists between the English and American Negro populations with respect to multiple molecular forms of phosphoglucomutase in erythrocytes. As in the English population, 2 autosomal loci, 1 of which comprise a polymorphic system, is present in the Negro. The only variant alleles observed which have effected the other locus seem to be similar in the Negro and Caucasian populations. The polymorphic system involving phosphoglucomutase in the Negro is probably not due to Caucasian admixture. This may not be the case with the adenylate kinase system, in which the rarer of the 2 alleles in the American Negro may be due to admixture. Further data on the frequencies of the various acid phosphatase phenotypes in the American Negro are also presented.