Zoonotic Transmission of Two New Strains of Human T-lymphotropic Virus Type 4 in Hunters Bitten by a Gorilla in Central Africa

Abstract
Molecular screening of 300 people at risk from Central Africa identified two HTLV-4 infected individuals. A zoonotic origin of infection was strongly suggested as both individuals reported being severely bitten by a gorilla during hunting activities. One strain was highly divergent and could be designated as the HTLV-4 subtype-b prototype.
Funding Information
  • Institut Pasteur
  • Investissement d'Avenir
  • Laboratoire d'Excellence (LABEX)
  • Integrative Biology of Emerging Infectious Diseases
  • Bourse de l′Ecole Normale Supérieure, Faculté Paris Diderot
  • EU PF7 EDENext (n°261504)
  • EMPERIE (n°223498)
  • Service de Coopération et de l'Action Culturelle of the French Embassy in Yaounde
  • Institut National pour le Cancer
  • Virus Cancer Prevention Association in Paris, France
  • Centre International de Recherches Médicales de Franceville, funded by the Gabonese Government, Total Gabon, and the French Foreign Ministry