Intradermal Histamine Releasing Effect Caused by Org-NC 45 A Comparison with Pancuronium, Metocurine and d-Tubocurarine
- 1 October 1980
- journal article
- research article
- Published by Wiley in Acta Anaesthesiologica Scandinavica
- Vol. 24 (5), 393-394
- https://doi.org/10.1111/j.1399-6576.1980.tb01568.x
Abstract
Histamine release caused by Org-NC 45, pancuronium, metocurine and d-tubocurarine was determined by measuring the diameter of the redness and skin induration following the intradermal injection of these drugs. d-Tubocurarine and metocurine caused the largest diameter of redness and induration, followed by pancuronium. Org-NC 45 caused the smallest reaction. We conclude that Org-NC 45 may be the drug of choice in patients with asthma and allergic reactions.Keywords
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