Response to Nocturnal Alarms Using a Real-Time Glucose Sensor
- 1 June 2005
- journal article
- research article
- Published by Mary Ann Liebert Inc in Diabetes Technology & Therapeutics
- Vol. 7 (3), 440-447
- https://doi.org/10.1089/dia.2005.7.440
Abstract
Background: The objective of this study was to determine how subjects responded to alarms for hypo- and hyperglycemia while they were sleeping. Research Design and Methods: Twenty subjects with type 1 diabetes (4–17 years old) were admitted to a clinical research center for approximately 24 h. Each subject wore two GlucoWatch ® G2™ Biographers (GW2B) (Cygnus, Inc., Redwood City, CA) and was videotaped using an infrared camera from 9 p.m. to 7 a.m. The videotapes were reviewed to determine if the GW2B alarms were audible on the tape and to document the subject's response to the alarms. Because many alarms can occur surrounding a change in blood glucose, GW2B alarm "events" are defined as a one or more alarms separated from previous alarms by more than 30 min. Results: Downloaded data from the biographers identified 240 individual alarms, 75% of which occurred while the subject was sleeping. Of the 240 alarms 68% were audible on the videotape. Subjects awoke to 29% of individual alarms and to 66% of alarm events. Subjects 4–6 years old responded to 17% of alarms, 7–11 year olds responded to 20% of alarms, adolescents responded to 53% of alarms, and parents responded to 37% of alarms. Subjects awoke to 40% of the first alarm during the night, but to only 28% of subsequent alarms. There were 11 events when the glucose was confirmed to be ≤70 mg/dL, and in each case the subject was awoken. Fifty-five percent of alarm events occurred when there was no hypo- or hyperglycemia confirmed by a reference glucose value. Conclusions: Subjects awoke to 29% of individual alarms and to 66% of alarm events. Subjects awoke during all alarm events when hypoglycemia was confirmed, but there was a high incidence of false alarms.Keywords
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