Prevalence of vernal keratoconjunctivitis and its associated factors among children in Gambella town, southwest Ethiopia, June 2018
Open Access
- 18 April 2019
- journal article
- research article
- Published by Public Library of Science (PLoS) in PLOS ONE
- Vol. 14 (4), e0215528
- https://doi.org/10.1371/journal.pone.0215528
Abstract
Vernal keratoconjunctivitis is a chronic bilateral severe form of allergic conjunctivitis which affects normal activities in school/work. It is a severe form of allergies in warm and dry tropical and sub-tropical countries. Its prevalence in Ethiopia ranges from 5.2% to7.3%. Most studies are institution based and do not address specific factors associated with vernal keratoconjunctivitis. There is no a study that shows the magnitude of vernal keratoconjunctivitis in the study area. To assess the prevalence of vernal keratoconjunctivitis and its associated factors among children in Gambella town, Southwest Ethiopia, 2018. A community based cross-sectional study was conducted from April 25 to May 12, 2018, in Gambella town. A total of 578 study participants were selected using a systematic random sampling technique. A pre-tested semi-structured questionnaire, torch, and magnifying loop were used to collect data. The data was entered into epidemiological information 7.1 and exported to statistical package for social science for analysis. Binary logistic regression analysis model was fitted to identify factors associated with vernal keratoconjunctivitis. Odds ratio with respected 95% CI was used to identify the direction and strength of association. A total of 574 children participated in this study representing a response rate of 99.30%. The mean age of the participants was 9.74±4.0 years. The prevalence of vernal keratoconjunctivitis was 11.10% (95% CI: 8.70, 13.90). Male sex (adjusted odds ratio = 4.12(95% CI: 1.42, 11.91)), close animal contact (adjusted odds ratio = 3.45(95% CI: 1.14, 10.41)), dust exposure (adjusted odds ratio = 3.38(95% CI: 1.31, 10.04)), and personal systemic allergy history (adjusted odds ratio = 4.82(1.40, 16.72) were independently associated with vernal keratoconjunctivitis. The prevalence of VKC was high among children in Gambella town. Sex being male, close animal contact, personal systemic allergy history, and dust exposure were positively associated with vernal keratoconjunctivitis independently.This publication has 36 references indexed in Scilit:
- Allergic conjunctivitis: a comprehensive review of the literatureItalian Journal of Pediatrics, 2013
- Vernal Keratoconjunctivitis in School Children in Rwanda: Clinical Presentation, Impact on School Attendance, and Access to Medical CareOphthalmology, 2012
- Vernal Keratoconjunctivitis in School Children in Rwanda and Its Association with Socio-Economic Status: A Population-Based SurveyThe American Journal of Tropical Medicine and Hygiene, 2011
- Vernal keratoconjunctivitis: a major reviewActa Ophthalmologica, 2009
- Prospective, Multicenter Demographic and Epidemiological Study on Vernal Keratoconjunctivitis: A Glimpse of Ocular Surface in Italian PopulationOphthalmic Epidemiology, 2009
- Prevalence of vernal keratoconjunctivitis: a rare disease?British Journal of Ophthalmology, 2008
- Chronic allergic Conjunctivitis: An evaluation of the role of family history and atopyAnnals of Ibadan Postgraduate Medicine, 2007
- Vernal keratoconjunctivitisEye, 2004
- Vernal keratoconjunctivitis revisited: A case series of 195 patients with long-term followupOphthalmology, 2000
- A survey of vernal keratoconjunctivitis and other eosinophil-mediated external eye diseases amongst PalestiniansOphthalmic Epidemiology, 2000