RUNX1 Is a Key Target in t(4;11) Leukemias that Contributes to Gene Activation through an AF4-MLL Complex Interaction
Open Access
- 31 January 2013
- journal article
- Published by Elsevier BV in Cell Reports
- Vol. 3 (1), 116-127
- https://doi.org/10.1016/j.celrep.2012.12.016
Abstract
No abstract availableKeywords
This publication has 73 references indexed in Scilit:
- Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemiaNature, 2011
- RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemiaNature, 2011
- MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1LCancer Cell, 2011
- t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLLLeukemia Research, 2011
- Multiple Interactions Recruit MLL1 and MLL1 Fusion Proteins to the HOXA9 Locus in LeukemogenesisMolecular Cell, 2010
- The PAF Complex Synergizes with MLL Fusion Proteins at HOX Loci to Promote LeukemogenesisCancer Cell, 2010
- A Higher-Order Complex Containing AF4 and ENL Family Proteins with P-TEFb Facilitates Oncogenic and Physiologic MLL-Dependent TranscriptionCancer Cell, 2010
- AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to LeukemiaMolecular Cell, 2010
- H3K79 Methylation Profiles Define Murine and Human MLL-AF4 LeukemiasCancer Cell, 2008
- Unique and Independent Roles for MLL in Adult Hematopoietic Stem Cells and ProgenitorsCell Stem Cell, 2007