Knockout of the Mouse Glutamate Cysteine Ligase Catalytic Subunit (Gclc) Gene: Embryonic Lethal When Homozygous, and Proposed Model for Moderate Glutathione Deficiency When Heterozygous
- 1 December 2000
- journal article
- Published by Elsevier BV in Biochemical and Biophysical Research Communications
- Vol. 279 (2), 324-329
- https://doi.org/10.1006/bbrc.2000.3930
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- Regulation ofγ-glutamylcysteine synthetase subunit gene expression: Insights into transcriptional control of antioxidant defensesFree Radical Research, 2000
- Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosisBiochemical Pharmacology, 1999
- [3] Glutathione biosynthesis and its inhibitionMethods in enzymology, 1995
- [1] Glutathione metabolismMethods in enzymology, 1995
- Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapyPharmacology & Therapeutics, 1991
- Cellular glutathione as a determinant of sensitivity to mercuric chloride toxicity: Prevention of toxicity by giving glutathione monoesterBiochemical Pharmacology, 1990
- Relationship between intracellular GSH levels and hypoxic cell radiosensitivityPharmacology & Therapeutics, 1988
- Glutathione, a first line of defense against cadmium toxicityThe FASEB Journal, 1987
- GLUTATHIONEAnnual Review of Biochemistry, 1983
- Glutathione export by human lymphoid cells: depletion of glutathione by inhibition of its synthesis decreases export and increases sensitivity to irradiation.Proceedings of the National Academy of Sciences, 1981