Loss of sclerostin promotes osteoarthritis in mice via β-catenin-dependent and -independent Wnt pathways
Open Access
- 6 February 2015
- journal article
- Published by Springer Science and Business Media LLC in Arthritis Research & Therapy
- Vol. 17 (1), 24-11
- https://doi.org/10.1186/s13075-015-0540-6
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- Pathogenesis and epidemiology of osteoarthritis.2013
- Load Regulates Bone Formation and Sclerostin Expression through a TGFβ-Dependent MechanismPLOS ONE, 2013
- Bone remodelling in osteoarthritisNature Reviews Rheumatology, 2012
- Articular Cartilage Degradation in OsteoarthritisHSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery, 2012
- Studying Gene Expression in Bone by In Situ HybridizationPublished by Springer Science and Business Media LLC ,2011
- Increased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritisOsteoarthritis and Cartilage, 2011
- Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation MiceJournal of Bone and Mineral Research, 2009
- Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone StrengthJournal of Bone and Mineral Research, 2008
- LDL Receptor-Related Protein 5 (LRP5) Affects Bone Accrual and Eye DevelopmentCell, 2001
- Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in aG-protein-dependent mannerCurrent Biology, 1999