Abstract
A decade ago most physicians had become convinced that treatment of moderate or severe hypertension with appropriate antihypertensive drugs would not only lower blood pressure but would also reduce overall morbidity and mortality from cardiovascular disease. The most impressive evidence in support of this view was the Veterans Administration Cooperative Study,1 2 3 a randomized, double-blind, placebo-controlled trial in over 500 middle-aged men, showing that drug treatment lowered the incidence of morbid events among those with moderate or severe hypertension. Although drugs also tended to lower morbidity and mortality among men with mild hypertension (diastolic blood pressure of 90 to 104 mm . . .