The Nature of Hairy Cells - A Study with a Panel of Monoclonal Antibodies
- 24 April 2009
- journal article
- research article
- Published by Wiley in Scandinavian Journal of Haematology
- Vol. 30 (3), 223-226
- https://doi.org/10.1111/j.1600-0609.1983.tb01479.x
Abstract
In all 11 patients with hairy-cell leukemia (HCL) tested, a high percentage of peripheral blood and splenic (3 cases) hairy cells (HC) reacted with 2 B-cell-specific monoclonal antibodies (FMC1 and FMC7) but failed to stain with 5 monocyte/macrophage-specific (FMC17, UCHM1, SM1, SM.phi. and OKM1) and with 4 T-cell-specific antibodies (UCHT1, Leu1, 2a and 3a). The data provide further evidence supporting the B-cell nature of the HC of HCL.Keywords
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