The Regulation of Hemostasis: The Protein C System
- 15 May 1986
- journal article
- review article
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 314 (20), 1298-1304
- https://doi.org/10.1056/nejm198605153142006
Abstract
We speak very frequently of the normal clotting time. In a glass tube?... Glass tubes have held the center of the stage for quite a long time but the process of clotting is now observed in plastic vessels and a considerably longer period of time is required than when glass is used.... If the same blood were kept outside the body in a test tube made from a vein or artery it would take a very long time to clot.— Charles H. Best, 19481 EXTENSIVE investigation into the mechanisms of blood clotting has yielded substantial insights into the process . . .Keywords
This publication has 42 references indexed in Scilit:
- The Role of Fibrin Monomer and an in vivo Thrombin-Induced Anticoagulant in Experimental Venous ThrombosisScandinavian Journal of Haematology, 2009
- Recurrent Venous Thromboembolism in Patients with a Partial Deficiency of Protein SThe New England Journal of Medicine, 1984
- HEREDITARY DYSFUNCTIONAL PROTEIN C (PROTEIN C BERGAMO) AND THROMBOSISThe Lancet, 1984
- Activated Protein C InhibitorSeminars in Thrombosis and Hemostasis, 1984
- Homozygous Protein C Deficiency Manifested by Massive Venous Thrombosis in the NewbornThe New England Journal of Medicine, 1984
- Congenital Protein C Deficiency and Venous ThromboembolismThe New England Journal of Medicine, 1983
- PROTEIN C CONCENTRATES FOR THERAPEUTIC USEThe Lancet, 1983
- Evidence of normal functional levels of activated protein C inhibitor in combined Factor V/VIII deficiency disease.JCI Insight, 1982
- DEFICIENCIES OF PROTEIN C, AN INHIBITOR OF BLOOD COAGULATIONThe Lancet, 1982
- Deficiency of protein C inhibitor in combined factor V/VIII deficiency disease.JCI Insight, 1980