Studies on the Constituents of Leonurus sibiricus L.
- 1 January 2003
- journal article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 51 (3), 341-342
- https://doi.org/10.1248/cpb.51.341
Abstract
Two new furanoditerpene-lactones, LS-1 (1) and LS-2 (2), were isolated along with four known furanoditerpene-lactones 3, 4, 5 and 6 from the aerial part of Leonurus sibiricus L. The structures of the new compounds were determined by spectroscopic means. Compounds 1—6 isolated here exhibited moderate cytotoxic activity (IC50=50—60 μg/ml) against leukemia cells (L 1210) in tissue culture.Keywords
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