The Spectrum of Renal Disease in Laurence–Moon–Biedl Syndrome

Abstract

To determine the nature, extent, and severity of renal involvement in Laurence–Moon–Biedl syndrome (obesity, mental retardation, polydactyly, hypogonadism, and pigmented retinal dystrophy), we evaluated 20 of 30 patients with the disorder identified from ophthalmologic records in Newfoundland. The mean age was 31 years, and seven were male.