Inhaled Nitric Oxide for the Adult Respiratory Distress Syndrome
Open Access
- 11 February 1993
- journal article
- clinical trial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 328 (6), 399-405
- https://doi.org/10.1056/nejm199302113280605
Abstract
The adult respiratory distress syndrome is characterized by pulmonary hypertension and right-to-left shunting of venous blood. We investigated whether inhaling nitric oxide gas would cause selective vasodilation of ventilated lung regions, thereby reducing pulmonary hypertension and improving gas exchange.This publication has 34 references indexed in Scilit:
- Bronchodilator action of inhaled nitric oxide in guinea pigs.JCI Insight, 1992
- Inhaled Nitric Oxide A Selective Pulmonary Vasodilator of Heparin-Protamine Vasoconstriction in SheepAnesthesiology, 1991
- Prostacyclin for the Treatment of Pulmonary Hypertension in the Adult Respiratory Distress SyndromeAnesthesiology, 1990
- Prostaglandin E1 and Nitroglycerin Reduce Pulmonary Capillary Pressure but Worsen Ventilation—Perfusion Distributions in Patients with Adult Respiratory Distress SyndromeAnesthesiology, 1989
- Vascular endothelial cells synthesize nitric oxide from L-arginineNature, 1988
- Comparison of Ketanserin and Sodium Nitroprusside in Patients with Severe ARDSAnesthesiology, 1988
- The Effect of Nitroprusside on Pulmonary Edema, Oxygen Exchange, and Blood Flow in Hydrochloric Acid AspirationAnesthesiology, 1987
- The pathophysiology of failure in acute right ventricular hypertension: hemodynamic and biochemical correlations.Circulation, 1981
- Pulmonary Hypertension in Severe Acute Respiratory FailureNew England Journal of Medicine, 1977
- Increased Sheep Lung Vascular Permeability Caused by Pseudomonas BacteremiaJCI Insight, 1974