Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2–P2X7 pathway
Open Access
- 25 October 2010
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 207 (12), 2561-2568
- https://doi.org/10.1084/jem.20091154
Abstract
Extracellular NAD+ affects the survival and function of regulatory T cells, and NAD-mediated depletion of regulatory T cells promotes anti-tumor responses in mice.Keywords
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