Lung Cancer Induced in Hamsters by Low Doses of Alpha Radiation from Polonium-210
- 16 May 1975
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 188 (4189), 737-738
- https://doi.org/10.1126/science.1124396
Abstract
Lung cancers have been induced in 9 to 53 percent of hamsters given multiple intratracheal instillations of polonium-210 in amounts yielding lifetime exposures of 15 to 300 rads to the lungs. Cigarette smokers have previously been estimated to receive 20 rads to areas of the bronchial epithelium from deposited polonium-210. This finding thus supports the hypothesis that alpha radiation resulting from the polonium-210 or lead-210 present in cigarette smoke may be a significant causative factor in human lung cancer.Keywords
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