Human plasma thrombopoietin levels are regulated by binding to platelet thrombopoietin receptors in vivo
- 1 March 2002
- journal article
- research article
- Published by Wiley in Transfusion
- Vol. 42 (3), 321-327
- https://doi.org/10.1046/j.1537-2995.2002.00047.x
Abstract
BACKGROUND: Data from several studies support the hypothesis that thrombopoietin (TPO) plasma levels are regulated via circulating platelet (PLT) numbers by binding to PLT TPO receptors (TPO‐Rs). In...This publication has 31 references indexed in Scilit:
- Analysis of the kinetics of TPOuptake during platelet transfusionTransfusion, 2001
- The role of platelet α-granular proteins in the regulation of thrombopoietin messenger RNA expression in human bone marrow stromal cellsBlood, 2000
- Autoantibodies neutralizing thrombopoietin in a patient with a megakaryocytic thrombocytopenic purpuraBlood, 2000
- Thrombopoietin induces rapid resolution of thrombocytopenia after orthotopic liver transplantation through increased platelet productionBlood, 2000
- ThrombopoietinNew England Journal of Medicine, 1998
- Thrombopoietin levels after chemotherapy and in naturally occurring human diseasesCurrent Opinion in Hematology, 1998
- Serum thrombopoietin levels in patients correlate inversely with platelet counts during chemotherapy-induced thrombocytopeniaLeukemia, 1998
- Localization and Regulation of Thrombopoietin mRNA Expression in Human Kidney, Liver, Bone Marrow, and Spleen Using In Situ HybridizationBlood, 1997
- Megakaryocyte growth and development factor. Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy-induced thrombocytopenia.JCI Insight, 1995
- The purification of megapoietin: a physiological regulator of megakaryocyte growth and platelet production.Proceedings of the National Academy of Sciences of the United States of America, 1994