Long‐term accumulation and microdistribution of uranium in the bone and marrow of beagle dog
- 1 August 2004
- journal article
- other
- Published by Taylor & Francis Ltd in International Journal of Radiation Biology
- Vol. 80 (8), 567-575
- https://doi.org/10.1080/09553000410001723884
Abstract
The accumulation and microdistribution of uranium in the bone and marrow of Beagle dogs were determined by both neutron activation and neutron‐fission analysis. The experiment started immediately after the weaning period, lasting till maturity. Two animal groups were fed daily with uranyl nitrate at concentrations of 20 and 100 µg g−1 food. Of the two measuring techniques, uranium accumulated along the marrow as much as in the bone, contrary to the results obtained with single, acute doses. The role played by this finding for the evaluation of radiobiological long‐term risks is discussed. It was demonstrated, by means of a biokinetical approach, that the long‐term accumulation of uranium in bone and marrow could be described by a piling up of single dose daily incorporation.Keywords
This publication has 10 references indexed in Scilit:
- A Biokinetic Model for Alpha-emitting Bone Surface-seeking Radionuclides in the Mouse SkeletonRadiation Protection Dosimetry, 2000
- Temporal change in microdosimetry to bone marrow and stromal progenitor cells from alpha-particle-emitting radionuclides incorporated in bone.Radiation Research, 1999
- Effect of Biophosphonates on Abnormal Mandibular Growth of Rats Intoxicated with UraniumHealth Physics, 1998
- Fat Cells in Red Bone Marrow of Human Rib: Their Size and Spatial Distribution with Respect to the Radon-derived Dose to the Haemopoietic TissueInternational Journal of Radiation Biology, 1995
- TASTRAK Spectroscopy of Polonium-210 Alpha-Particle Activity at Bone Surfaces: Evidence for a Concentrated Surface Deposit Less Than 3 μm DeepRadiation Research, 1994
- Dose to red bone marrow from natural radon and thoron exposureThe British Journal of Radiology, 1991
- The architecture of bone marrow cell populationsThe International Journal of Cell Cloning, 1990
- Cancer Incidence and Lifespan Vs. Alpha-particle Dose in BeaglesHealth Physics, 1987
- Further Studies on the Absorption of Actinide Elements from the Gastrointestinal Tract of Neonatal AnimalsHealth Physics, 1982
- Absorption of Actinide Elements From the Gastrointestinal Tract of Rats, Guinea Pigs and DogsHealth Physics, 1980