Highly Efficient Heck Reactions of Aryl Bromides with n-Butyl Acrylate Mediated by a Palladium/Phosphine−Imidazolium Salt System
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- 26 April 2001
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 3 (10), 1511-1514
- https://doi.org/10.1021/ol015827s
Abstract
A new phosphine−imidazolium salt, L·HBr (1, L = (1-ethylenediphenylphosphino-3-(mesityl))imidazol-2-ylidene), has been prepared. A combination of 0.5 mol % of Pd(dba)2 and 0.5 mol % of L·HBr in the presence of 2 equiv of Cs2CO3 as base has proven to be highly efficient in the Heck coupling reactions of aryl bromides (from electron-deficient to electron-rich aryl bromides) with n-butyl acrylate.This publication has 33 references indexed in Scilit:
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