Notch Signaling
Open Access
- 1 October 2012
- journal article
- review article
- Published by Cold Spring Harbor Laboratory in Cold Spring Harbor Perspectives in Biology
- Vol. 4 (10), a011213
- https://doi.org/10.1101/cshperspect.a011213
Abstract
When the cell-surface receptor Notch interacts with a ligand (e.g., Delta), its intracellular domain is cleaved and travels to the nucleus to regulate transcription. This influences cell division, fate, and death in metazoans.Keywords
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