α4 integrins and the immune response
- 1 August 2002
- journal article
- review article
- Published by Wiley in Immunological Reviews
- Vol. 186 (1), 118-124
- https://doi.org/10.1034/j.1600-065x.2002.18611.x
Abstract
Summary: The α4 integrins (α4β1 and α4β7) play multiple roles in the immune system. α4 integrins impact hematopoiesis, leukocyte trafficking in immune surveillance and inflammation, and leukocyte act...Keywords
This publication has 91 references indexed in Scilit:
- A Fragment of Paxillin Binds the α4Integrin Cytoplasmic Domain (Tail) and Selectively Inhibits α4-Mediated Cell MigrationJournal of Biological Chemistry, 2002
- Signal Transduction by Cell Adhesion Receptors and the Cytoskeleton: Functions of Integrins, Cadherins, Selectins, and Immunoglobulin-Superfamily MembersAnnual Review of Pharmacology and Toxicology, 2002
- Paxillin Binding to a Conserved Sequence Motif in the α4 Integrin Cytoplasmic DomainJournal of Biological Chemistry, 2000
- The α4-integrin: an alternative pathway for neutrophil recruitment?Immunology Today, 1999
- Dissection of Pathways Implicated in Integrin-mediated Actin Cytoskeleton AssemblyJournal of Biological Chemistry, 1997
- Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation.The Journal of cell biology, 1996
- Cell adhesion and migration are regulated at distinct stages of thymic T cell development: the roles of fibronectin, VLA4, and VLA5.The Journal of Experimental Medicine, 1996
- Integrins: Emerging Paradigms of Signal TransductionAnnual Review of Cell and Developmental Biology, 1995
- Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient miceNature, 1995
- The pathophysiologic role of alpha 4 integrins in vivo.JCI Insight, 1994