The neurovirulence and neuroinvasiveness of chimeric tick-borne encephalitis/dengue virus can be attenuated by introducing defined mutations into the envelope and NS5 protein genes and the 3′ non-coding region of the genome
- 1 July 2010
- journal article
- research article
- Published by Elsevier BV in Virology
- Vol. 405 (1), 243-252
- https://doi.org/10.1016/j.virol.2010.06.014
Abstract
No abstract availableKeywords
This publication has 40 references indexed in Scilit:
- NS5 of Dengue Virus Mediates STAT2 Binding and DegradationJournal of Virology, 2009
- Tick-borne flaviviruses: dissecting host immune responses and virus countermeasuresImmunologic Research, 2008
- Evaluation of St. Louis encephalitis virus/dengue virus type 4 antigenic chimeric viruses in mice and rhesus monkeysVaccine, 2008
- Comparative Neuropathogenesis and Neurovirulence of Attenuated Flaviviruses in Nonhuman PrimatesJournal of Virology, 2008
- Evaluation of the Langat/dengue 4 chimeric virus as a live attenuated tick-borne encephalitis vaccine for safety and immunogenicity in healthy adult volunteersVaccine, 2008
- Identification of Residues Critical for the Interferon Antagonist Function of Langat Virus NS5 Reveals a Role for the RNA-Dependent RNA Polymerase DomainJournal of Virology, 2007
- Tick-borne Encephalitis – a European Health Challenge Conference report of the 8th meeting of the International Scientific Working Group on Tick-borne Encephalitis (ISW TBE)Wiener Medizinische Wochenschrift, 2006
- A Tick-Borne Langat Virus Mutant That Is Temperature Sensitive and Host Range Restricted in Neuroblastoma Cells and Lacks Neuroinvasiveness for Immunodeficient MiceJournal of Virology, 2006
- Steps of the tick-borne encephalitis virus replication cycle that affect neuropathogenesisVirus Research, 2005
- Yellow Fever VaccinesBiologicals, 1997