Endogenous porphyrin fluorescence in tumors
- 1 January 1987
- journal article
- research article
- Published by Wiley in Lasers in Surgery and Medicine
- Vol. 7 (6), 467-472
- https://doi.org/10.1002/lsm.1900070605
Abstract
The fluorescence of endogenous porphyrins in tumors has been attributed to the presence of several different species of bacteria inhabiting ulcerated and necrotic tissues. We have examined this “autofluorescence” in carcinogen-induced tumors in the hamster oral mucosa and in patients with cancer of the oral cavity. In several instances, bright autofluorescence of normal tissues has been observed. This represents a potential false-positive identification of cancer when systemic hematoporphyrin derivative fluorescence is used as a diagnostic technique.Keywords
This publication has 18 references indexed in Scilit:
- Porphyrin Fluorescence and Photosensitization in Head and Neck CancerJAMA Otolaryngology–Head & Neck Surgery, 1986
- FLUORESCENT MICROSCOPY OF HEMATOPORPHYRIN DERIVATIVE IN THE NUDE MOUSE TUMOR MODELThe Laryngoscope, 1986
- FLUORESCENCE SPECTRAL CHANGES OF HEMATOPORPHYRIN DERIVATIVE UPON BINDING TO LIPID VESICLES, Staphylococcus aureus AND Escherichia coli CELLSPhotochemistry and Photobiology, 1985
- Fluorescence of experimental atheromatous plaques with hematoporphyrin derivative.JCI Insight, 1983
- Fluorescence Fiberoptic Bronchoscopy in the Diagnosis of Early Stage Lung CancerPublished by Springer Science and Business Media LLC ,1982
- Hematoporphyrin-Derivative Fluorescence in Malignant NeoplasmsAnnals of Surgery, 1968
- Mechanisms involved in the production of red fluorescence of human and experimental tumoursThe Journal of Pathology and Bacteriology, 1963
- Porphyrin Fluorescence of Experimentally produced Squamous Cell CarcinomaNature, 1960
- Red fluorescence of experimentally induced and human tumoursThe Journal of Pathology and Bacteriology, 1960
- Experimental Carcinogenesis in the Cheek Pouch of the Syrian HamsterJournal of Dental Research, 1954