Depression and health-related quality of life in people with coronary heart disease: a systematic review
- 28 March 2012
- journal article
- review article
- Published by Oxford University Press (OUP) in European Journal of Cardiovascular Nursing
- Vol. 11 (3), 265-275
- https://doi.org/10.1177/1474515111430928
Abstract
Depression affects 20% of people with coronary heart disease (CHD) and predicts worse health-related quality of life (HRQoL), but in primary studies the strength of this reported relationship has been inconsistent. We conducted a systematic review to investigate the extent to which depression independently predicts subsequent physical HRQoL. We searched electronic databases (MEDLINE, PsycINFO, CINAHL and EMBASE) to identify prospective cohort studies that included CHD patients, focused on depression and subsequent physical HRQoL using standardised measures. Included studies were assessed for methodological quality. We identified 11 independent studies, of which nine showed a significant association between depression and subsequent physical HRQoL. There was no systematic methodological difference between those studies that did and did not show a significant association; in particular the results did not appear to be affected by the way depression or physical HRQoL was measured. Five of the 11 studies were of moderate to high methodological quality and controlled for both HRQoL and the severity of CHD at baseline. Four studies showed a significant association between depression and HRQoL. Depression predicts subsequent physical HRQoL and this association was not attributable to confounding effects of baseline HRQoL or the severity of the CHD. Identification of depressed CHD patients may improve targeting of resources at people at increased risk of worse physical HRQoL. Treating depression may improve subsequent physical HRQoL, though this needs to be established in future randomised controlled trials.Keywords
This publication has 39 references indexed in Scilit:
- Depression in Patients with Coronary Heart DiseaseAmerican Journal Of Medicine, 2008
- New Onset Depression Following Myocardial Infarction Predicts Cardiac MortalityPsychosomatic Medicine, 2008
- Only Incident Depressive Episodes After Myocardial Infarction Are Associated With New Cardiovascular EventsJournal of the American College of Cardiology, 2006
- Depression as an aetiologic and prognostic factor in coronary heart disease: a meta-analysis of 6362 events among 146 538 participants in 54 observational studiesEuropean Heart Journal, 2006
- Depression as a Risk Factor for Mortality in Patients With Coronary Heart Disease: A Meta-analysisPsychosomatic Medicine, 2004
- One year cumulative incidence of depression following myocardial infarction and impact on cardiac outcomeJournal of Psychosomatic Research, 2004
- The Significance of Depression in Older Patients After Myocardial InfarctionJournal of the American Geriatrics Society, 2002
- Depression and 18-Month Prognosis After Myocardial InfarctionCirculation, 1995
- The Nature and Course of Depression Following Myocardial InfarctionArchives of Internal Medicine, 1989
- Major depressive disorder predicts cardiac events in patients with coronary artery disease.Psychosomatic Medicine, 1988