Multiple Myeloma and Epidural Spinal Cord Compression : Case Presentation and a Spine Surgeon's Perspective
Open Access
- 1 January 2013
- journal article
- Published by Korean Neurosurgical Society in Journal of Korean Neurosurgical Society
- Vol. 54 (2), 151-154
- https://doi.org/10.3340/jkns.2013.54.2.151
Abstract
Multiple myeloma, a multicentric hematological malignancy, is the most common primary tumor of the spine. As epidural myeloma causing spinal cord compression is a rare condition, its therapeutic approach and clinical results have been reported to be diverse, and no clear guidelines for therapeutic decision have been established. Three patients presented with progressive paraplegia and sensory disturbance. Image and serological studies revealed multiple myeloma and spinal cord compression caused by epidural myeloma. Emergency radiotherapy and steroid therapy were performed in all three cases. However, their clinical courses and results were distinctly different. Following review of our cases and the related literature, we suggest a systematic therapeutic approach for these patients to achieve better clinical results.Keywords
This publication has 17 references indexed in Scilit:
- Cervical epidural plasmacytoma presenting as ascending paraparesisThe Spine Journal, 2011
- Isolated extraosseous epidural myeloma presenting with thoracic compressive myelopathyThe Spine Journal, 2010
- Clinical Outcomes after Percutaneous Vertebroplasty for Pathologic Compression Fractures in Osteolytic Metastatic Spinal DiseaseJournal of Korean Neurosurgical Society, 2009
- Single fraction spine radiosurgery for myeloma epidural spinal cord compression.2009
- Extraosseous epidural multiple myeloma presenting with thoracic spine compressionJoint Bone Spine, 2008
- Features of extramedullary and extraosseous multiple myeloma: a report of 19 patients from a single centerEuropean Journal of Haematology, 2004
- Multiple Myeloma: Surgery of the SpineSpine, 2002
- Extraosseous Epidural Tumor of Immunoglobulin D MyelomaJournal of SPINAL DISORDERS, 1992
- Spinal-cord compression in myeloma.BMJ, 1979
- MYELOMATOSISThe Lancet, 1961