Direct Evidence for Peptide Transporter (PepT1)-Mediated Uptake of a Nonpeptide Prodrug, Valacyclovir
- 18 September 1998
- journal article
- Published by Elsevier BV in Biochemical and Biophysical Research Communications
- Vol. 250 (2), 246-251
- https://doi.org/10.1006/bbrc.1998.9298
Abstract
No abstract availableKeywords
Funding Information
- Core Research for Evolutional Science and Technology
- National Institutes of Health (AI33789, AI42007)
- Japan Science and Technology Corporation
- Ministry of Education, Culture, Sports, Science and Technology
This publication has 32 references indexed in Scilit:
- Valacyclovir: A Substrate for the Intestinal and Renal Peptide Transporters PEPT1 and PEPT2Biochemical and Biophysical Research Communications, 1998
- Carrier-mediated intestinal absorption of valacyclovir, the L-valyl ester prodrug of acyclovir. 1. Interactions with peptides, organic anions and organic cations in ratsBiopharmaceutics & Drug Disposition, 1998
- Selection of development candidates based on in vitro permeability measurementsAdvanced Drug Delivery Reviews, 1997
- Sequence, tissue distribution and developmental changes in rat intestinal oligopeptide transporterBiochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1996
- Absolute bioavailability and metabolic disposition of valaciclovir, the L-valyl ester of acyclovir, following oral administration to humansAntimicrobial Agents and Chemotherapy, 1995
- Human Intestinal H+/Peptide CotransporterPublished by Elsevier BV ,1995
- Expression cloning of a mammalian proton-coupled oligopeptide transporterNature, 1994
- Recurrent Selection for Test Weight and Grain Yield of OatCrop Science, 1993
- Acyclovir prodrugs: The road to valaciclovirDrugs of the Future, 1993
- Valaciclovir (BW256U87): The L-valyl ester of acyclovirJournal of Medical Virology, 1993