Callyspongamide A, a New Cytotoxic Polyacetylenic Amide from the Red Sea Sponge Callyspongia fistularis
- 8 May 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 66 (6), 861-862
- https://doi.org/10.1021/np0205809
Abstract
Callyspongamide A (1), a new cytotoxic polyacetylenic amide, has been isolated from the marine sponge Callyspongia fistularis collected in the Red Sea. Callyspongamide A is an amide derivative of a C(17)-polyacetylenic acid and phenethylamine. It represents a new class of secondary metabolites within the family Callyspongiidae. Its structure was determined on the basis of 1D and 2D (COSY, HOHAHA, HMQC, and HMBC) NMR studies and high-resolution mass spectral measurement.Keywords
This publication has 7 references indexed in Scilit:
- Callyspongynic Acid, a Polyacetylenic Acid Which Inhibits α-Glucosidase, from the Marine Sponge Callyspongia truncataJournal of Natural Products, 2002
- Antimycobacterial Polyynes of Devil's Club (Oplopanax horridus), a North American Native Medicinal PlantJournal of Natural Products, 1997
- Seven New Polyacetylene Derivatives, Showing Both Potent Metamorphosis-Inducing Activity in Ascidian Larvae and Antifouling Activity Against Barnacle Larvae, from the Marine Sponge Callyspongia truncataJournal of Natural Products, 1997
- Antitumor Activity and Stereochemistry of Acetylenic Alcohols from the Sponge Cribrochalina vasculumJournal of Natural Products, 1995
- Antifungal Brominated C18 Acetylenic Acids from the Marine Sponge, Petrosia volcano HoshinoTetrahedron, 1993
- Brominated Polyacetylenic Acids from the Marine Sponge Xestospongia muta: Inhibitors of HIV ProteaseJournal of Natural Products, 1992
- Naphthyl dioxetane phosphates: synthesis of novel substrates for enzymic chemiluminescent assaysThe Journal of Organic Chemistry, 1990