Emerging Mania Following Escitalopram Withdrawal in a Patient with Unipolar Depression Managed with its Reintroduction
- 1 May 2014
- journal article
- case report
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Psychiatric Practice
- Vol. 20 (3), 228-231
- https://doi.org/10.1097/01.pra.0000450323.37038.a9
Abstract
Discontinuation or withdrawal symptoms have been documented for all major classes of antide- pressants, especially the selective serotonin reuptake inhibitors (SSRIs). It has been reported that an antidepressant withdrawal syndrome may induce manic states in patients treated for major depression, even in the absence of a history of bipolar disorder. We report the case of a young woman with unipolar depression who developed a manic state after abrupt discontinuation of lowdose escitalopram. This manic state remitted when escitalopram was reintroduced within a week after the interruption of treatment.This publication has 8 references indexed in Scilit:
- Mania during antidepressant withdrawal in late‐onset depressionInternational Journal of Geriatric Psychiatry, 2013
- Antidepressant discontinuation manic states: a critical review of the literature and suggested diagnostic criteriaJournal of Psychopharmacology, 2010
- Antidepressant-Withdrawal ManiaPublished by Physicians Postgraduate Press, Inc ,2004
- Switch to Mania upon Discontinuation of Antidepressants in Patients with Mood Disorders: A Review of the LiteratureThe Canadian Journal of Psychiatry, 2003
- Mania associated with venlafaxine discontinuationInternational Journal of Neuropsychopharmacology, 2003
- Discontinuation Symptoms After Treatment With Serotonin Reuptake InhibitorsPublished by Physicians Postgraduate Press, Inc ,1997
- Paradoxical mood changes during pharmacotherapy of bipolar patientsBiological Psychiatry, 1990
- Hypomania after desipramine withdrawalAmerican Journal of Psychiatry, 1983