Fused Heterocycles: Synthesis of Some New Imidazo[1,2-a]- pyridine Derivatives
Open Access
- 30 September 2004
- Vol. 9 (10), 894-901
- https://doi.org/10.3390/91000894
Abstract
Some new thiazolidines and spirothiazolidines derived from hydrazones of2-methylimidazo[1,2-a]pyridine-3-carboxylic acid hydrazide, a bioisosteric derivative ofisoniazid, were synthesized and characterized by analytical, IR, 1H- and 13C-NMR andmass spectral data. Some of the newly synthesized compounds were screened for theirantimycobacterial activities. None of the tested compounds showed significant in vitroantituberculous activity at 6.25 μg/mL (MIC rifampin 0.031 μg/mL).This publication has 3 references indexed in Scilit:
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