Efficacy and Safety of Oral Pleconaril for Treatment of Colds Due to Picornaviruses in Adults: Results of 2 Double-Blind, Randomized, Placebo-Controlled Trials
Open Access
- 15 June 2003
- journal article
- clinical trial
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 36 (12), 1523-1532
- https://doi.org/10.1086/375069
Abstract
The novel capsid-binding antiviral pleconaril inhibits in vitro replication of most rhinoviruses and enteroviruses. Oral pleconaril treatment was stuKeywords
This publication has 31 references indexed in Scilit:
- Clinical Activity of Pleconaril in an Experimentally Induced Coxsackievirus A21 Respiratory InfectionThe Journal of Infectious Diseases, 2000
- Risk factors for lower respiratory complications of rhinovirus infections in elderly people living in the community: prospective cohort studyBMJ, 1996
- Detection of herpes simplex virus DNA in cerebrospinal fluid samples using the polymerase chain reaction and microplate hybridizationJournal of Virological Methods, 1996
- Detection of human rhinovirus RNA in nasal washings by PCRMolecular and Cellular Probes, 1993
- Respiratory viruses and exacerbations of asthma in adults.BMJ, 1993
- TREATMENT OF THE PICORNA VIRUS COMMON COLD BY INHIBITORS OF VIRAL UNCOATING AND ATTACHMENTAnnual Review of Microbiology, 1992
- Intranasal recombinant alfa-2b interferon treatment of naturally occurring common coldsAntimicrobial Agents and Chemotherapy, 1988
- Tables of the number of patients required in clinical trials using the logrank testStatistics in Medicine, 1982
- Improved Method for Collection of Nasal MucusThe Journal of Infectious Diseases, 1977
- Nonparametric Estimation from Incomplete ObservationsJournal of the American Statistical Association, 1958