The acellular dermal matrices (ADMs) are an alternative to autologous soft tissue transplants. They represent a scaffold for ingrowing blood vessels and cells, leading to a fast revascularization and tissue integration. However, the opinions regarding their performance and results can be easily divided. While some claim unsatisfactory results, there is an extensive literature support that confirms the opposite. Therefore, this short review summarizes several opinions and concludes that ADMs are suitable alternatives that can support predictable results.