Risk of Thyroid Neoplasms after Irradiation in Childhood
- 12 April 1968
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 160 (3824), 159-163
- https://doi.org/10.1126/science.160.3824.159
Abstract
The incidence of thyroid carcinoma and of clinically palpable thyroid nodules is compared in three groups of individuals many years after exposure to ionizing radiation in childhood or infancy. The estimated mean cumulative doses to the thyroid gland ranged from 20 rad in the Ann Arbor series irradiated with x-rays as infants for thymic enlargement upward to 1225 rad of mixed radiation (including that from ingested radioiodine) in the Marshallese children. Intermediate between these extremes is the high-risk subgroup in the Rochester series of persons irradiated for thymic enlargement; they received an estimated mean thyroid dose of 335 rad.Keywords
This publication has 8 references indexed in Scilit:
- NEOPLASMS IN THE ANN ARBOR SERIES OF THYMUS-IRRADIATED CHILDREN; A SECOND SURVEYAmerican Journal of Roentgenology, 1968
- Thyroid Abnormalities After Radiation Exposure in InfancyAnnals of Internal Medicine, 1967
- Thyroid Nodules as a Late Sequela of Radioactive FalloutNew England Journal of Medicine, 1966
- Goiter and Other Thyroid Diseases in Tecumseh, MichiganJAMA, 1965
- Effects Including Carcinogenesis of I131 and X-Rays on the Thyroid of Experimental AnimalsHealth Physics, 1963
- A Study of the Relationship Between X-ray Dose Delivered to the Thyroids of Children and the Subsequent Development of Malignant TumoursPhysics in Medicine & Biology, 1962
- Significance of Solitary Nontoxic Thyroid NodulesNew England Journal of Medicine, 1954
- Chronic Iodine Deficiency as Cause of Neoplasia in Thyroid and Pituitary of Aged RatsBritish Journal of Cancer, 1953