Loss of virulence in a small plaque mutant of the infectious bursal disease virus
- 1 March 1979
- journal article
- Published by Springer Science and Business Media LLC in Archiv für die gesamte Virusforschung
- Vol. 59 (1-2), 39-46
- https://doi.org/10.1007/bf01317893
Abstract
A variant strain Cu-1M was established from the infectious bursal disease virus strain Cu-1. This variant strain forms smaller plaques than the wild type; it has a retarded growth rate, does not lead to an overt disease in chickens and causes only minor lesions in the bursa of Fabricius. Infection with this strain induces solid protective immunity against infection with the virulent virus.Keywords
This publication has 7 references indexed in Scilit:
- The Significance of Influenza Virus Neuraminidase in ImmunityJournal of General Virology, 1974
- Isolation and characterization of two types of bluetongue virus particlesVirology, 1972
- Untersuchungen über die Biosynthese und über den serologischen Nachweis des Ribonucleoproteid-Antigens von InfluenzavirenMedical Microbiology and Immunology, 1971
- Chemical Fixation of Enzymes to Cyanogen Halide Activated Polysaccharide CarriersJBIC Journal of Biological Inorganic Chemistry, 1971
- [Studies on biosynthesis and serological demonstration of ribonucleoprotein antigen of influenza viruses. I. Studies on biosynthesis of RNP antigen and the role of cell nucleus in its synthesis].1971
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970
- Resolution of Multiple Ribonucleic Acid Species by Polyacrylamide Gel Electrophoresis*Biochemistry, 1967