Design and Implementation of Novel Multifunctional 3D Bioprinter
- 1 March 2016
- journal article
- research article
- Published by Mary Ann Liebert Inc in 3D Printing and Additive Manufacturing
- Vol. 3 (1), 64-68
- https://doi.org/10.1089/3dp.2015.0040
Abstract
3D bioprinting is a rapidly emerging biomedical variant of 3D printing technology. A 3D bioprinter could be defined as a robotic device for layer-by-layer biofabrication of 3D human tissues and organs from living cells and hydrogels according to a digital model. Development of commercial 3D bioprinters certifiable for clinical use will enable bioprinting 3D human tissues and organs suitable for implantation. The commercial multifunctional clinical 3D bioprinter of extrusion type suitable for robotic biofabrication of 3D human tissues and organs and potentially certifiable for clinical use is presented. The principle constructive feature of a 3D bioprinter is a separation of a cell printing process from hydrogel spraying, which allows the use of photo-sensitive hydrogel with ultraviolet-induced polymerization without cell damage. Some of its multiple potential functionalities have been tested and illustrated. Development of a clinical 3D bioprinter is an important step toward practical implementation of a highly desirable organ printing technology.Keywords
This publication has 9 references indexed in Scilit:
- Bioprinting scale-up tissue and organ constructs for transplantationTrends in Biotechnology, 2015
- 3D bioprinting of tissues and organsNature Biotechnology, 2014
- Printing and Prototyping of Tissues and ScaffoldsScience, 2012
- Organ printing: from bioprinter to organ biofabrication lineCurrent Opinion in Biotechnology, 2011
- Three-dimensional inkjet biofabrication based on designed imagesBiofabrication, 2011
- Organ printing: Tissue spheroids as building blocksBiomaterials, 2009
- Organ printing: promises and challengesRegenerative Medicine, 2008
- Direct Freeform Fabrication of Seeded Hydrogels in Arbitrary GeometriesTissue Engineering, 2006
- Organ printing: computer-aided jet-based 3D tissue engineeringTrends in Biotechnology, 2003