Abstract
This study was designed to determine the risk factors and long-term results of long-segment colon replacement or bypass of the entire thoracic esophagus. One hundred patients who underwent either long-segment colon replacement or bypass of the entire esophagus were studied. Nine per cent of the patients died in the hospital. There were seven instances of colon necrosis, and an additional seven instances of transient cervical esophagocolic anastomotic leaks. Necrosis of the colon was less frequent when the left colon was used as a substitute for the esophagus. The colon has proved to be a functional and durable substitute for the esophagus in 21 of the 100 patients, who have had their esophageal substitutes for more than five years.

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