Safety analysis of laparoscopic endoscopic cooperative surgery versus endoscopic submucosal dissection for selected gastric gastrointestinal stromal tumors: a propensity score-matched study

Abstract
Background Laparoscopic endoscopic cooperative surgery (LECS) is a safe alternative to endoscopic submucosal dissection (ESD) for select gastric gastrointestinal stromal tumors (GISTs) that are P = 0.029). LECS patients had less intraoperative bleeding than did ESD patients (15.0 ml [range 9.5–50.0 ml] vs. 43.5 ml [range 22.3–56.0 ml], P = 0.004). The two groups had similar postoperative courses. There was no difference in the reoperation rate between the two groups (P = 0.112). The ESD group had a shorter operating time than did the LECS group (41.5 min vs. 96.5 min, P < 0.001). However, during a follow-up of 57.9 (±28.9) months, the recurrence rate did not differ significantly between the two groups (0.0 vs. 6.7 %, respectively; P = 0.256). Conclusions LECS for selected gastric GIST patients is feasible and is associated with a better intraoperative outcome and an equal postoperative course compared with the results of ESD.
Funding Information
  • National High Technology Research and Development Program (863 Program) (No.2012AA011103)
  • The Development Center for Medical Science and Technology, the Ministry of Health of China (No.W2011 WAI44)
  • Major Program of Science and Technology Program of Guangzhou (No.201300000087)
  • The Research Fund of Public Welfare in Health Industry, Heath Ministry of China, (No.201402015)
  • Key Clinical Specialty Discipline Construction Program