Detection of Breast Cancer Microcalcifications Using a Dual-modality SPECT/NIR Fluorescent Probe
- 4 December 2008
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 130 (52), 17648-17649
- https://doi.org/10.1021/ja807099s
Abstract
Efficient chemical synthesis of a trifunctional, hydroxyapatite-binding molecule, which provides simultaneous in vivo imaging by NIR fluorescence and SPECT/CT has been described. Quantitation by SPECT provides the “gold standard” by which NIR fluorescence tomography of breast cancer microcalcifications can now be compared and optimized.Keywords
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