The Risk of Maternal Nutritional Depletion and Poor Outcomes Increases in Early or Closely Spaced Pregnancies
Open Access
- 1 May 2003
- journal article
- review article
- Published by Elsevier BV in Journal of Nutrition
- Vol. 133 (5), 1732S-1736S
- https://doi.org/10.1093/jn/133.5.1732s
Abstract
An adequate supply of nutrients is probably the single most important environmental factor affecting pregnancy outcome. Women with early or closely spaced pregnancies are at increased risk of entering a reproductive cycle with reduced reserves. Maternal nutrient depletion may contribute to the increased incidence of preterm births and fetal growth retardation among these women as well as the increased risk of maternal mortality and morbidity. In the past, it was assumed that the fetus functioned as a parasite and withdrew its nutritional needs from maternal tissues. Studies in both animals and humans demonstrate, however, that if the maternal nutrient supply is inadequate, the delicate balance between maternal and fetal needs is disturbed and a state of biological competition exists. Furthermore, maternal nutritional status at conception influences how nutrients are partitioned between the mother and fetal dyad. In severe deficiencies maternal nutrition is given preference; in a marginal state the fetal compartment is favored. Although the studies of nutrient partitioning have focused on energy and protein, the partitioning of micronutrients may also be influenced by the maternal nutritional status. Marginal intakes of iron and folic acid during the reproductive period induce a poor maternal status for these nutrients during the interpregnancy interval. Poor iron and folic acid status has also been linked to preterm births and fetal growth retardation. Supplementation with food and micronutrients during the interpregnancy period may improve pregnancy outcomes and maternal health among women with early or closely spaced pregnancies.Keywords
This publication has 31 references indexed in Scilit:
- Short interpregnancy intervals and unfavourable pregnancy outcome: role of folate depletionThe Lancet, 2001
- Effect of the interval between pregnancies on perinatal outcomes among white and black womenAmerican Journal of Obstetrics and Gynecology, 2001
- Effect of the Interval between Pregnancies on Perinatal OutcomesNew England Journal of Medicine, 1999
- The impact of short interpregnancy intervals on pregnancy outcomes in a low-income population.American Journal of Public Health, 1998
- Nutrition Issues and Adolescent PregnancyaNutrition Today, 1995
- Association of Young Maternal Age with Adverse Reproductive OutcomesNew England Journal of Medicine, 1995
- Lactation, seasonality, and mother's postpartum weight change in Bangladesh: An analysis of maternal depletionAmerican Journal of Human Biology, 1994
- Maternal weight status and term birth weight in first and second adolescent pregnanciesJournal of Adolescent Health, 1992
- A new definition of maternal depletion syndrome.American Journal of Public Health, 1992
- Postpartum nutritional status of Filipino womenAmerican Journal of Human Biology, 1992