AID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity
Open Access
- 21 June 2009
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature Structural & Molecular Biology
- Vol. 16 (7), 769-776
- https://doi.org/10.1038/nsmb.1623
Abstract
No abstract availableKeywords
This publication has 49 references indexed in Scilit:
- Estrogen directly activates AID transcription and functionThe Journal of Experimental Medicine, 2009
- The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammalsBMC Molecular Biology, 2008
- miR-181b negatively regulates activation-induced cytidine deaminase in B cellsThe Journal of Experimental Medicine, 2008
- Interaction between Antibody-Diversification Enzyme AID and Spliceosome-Associated Factor CTNNBL1Molecular Cell, 2008
- Molecular Mechanisms of Antibody Somatic HypermutationAnnual Review of Biochemistry, 2007
- Role of genomic instability and p53 in AID-induced c-myc–Igh translocationsNature, 2006
- Evolution of new nonantibody proteins via iterative somatic hypermutationProceedings of the National Academy of Sciences, 2004
- Generation and iterative affinity maturation of antibodies in vitro using hypermutating B-cell linesNature Biotechnology, 2002
- Affinity maturation and hypermutation in a simulation of the humoral immune responseEuropean Journal of Immunology, 1996
- Detection of recombinations between c-myc and immunoglobulin switch alpha in murine plasma cell tumors and preneoplastic lesions by polymerase chain reaction.Proceedings of the National Academy of Sciences of the United States of America, 1993